ABSTRACT
Backgrounds: The COVID-19 pandemic has brought an unprecedented healthy crisis to people worldwide. It is crucial to assess the psychological status of non-frontline nurses. More attention to the mental and physical health of non-frontline nurses during a public health emergency is necessary for a full understanding of the implications. Therefore, this study aims to investigate the factors that influence the acute stress reaction of non-frontline pediatric nurses during the COVID-19 pandemic. Methods: This study aimed to explore factors associated with acute stress reactions of non-frontline pediatric nurses in Hunan province during the COVID-19 pandemic. This was a cross-sectional design. Five hundred eighteen pediatric nurses from Hunan province, China, completed the Stanford Acute Stress Reaction Questionnaire (SASRQ), Depression Anxiety Stress Scales-21 (DASS-21), and Job Withdrawal Behavior Scales (JWB). Multiple linear regression analyses and Pearson's correlation were used to analyze the results. Results: The mean scores of DASS-21, JWB, SASRQ were 1.443 ± 0.500, 1.601 ± 0.544, and 1.858 ± 0.805, respectively. Stress, anxiety, depression (three sub-dimensions of DASS-21), JWB, monthly income and department were the major predictive factors for SASRQ (Adjusted R2 = 0.579, p < 0.001). Pearson's correlation showed that the mean score of SASRQ was positively correlated with JWB, DASS-21, and all its dimensions (p < 0.01). Conclusion: The study indicated that the SASRQ was greater with higher levels of DASS-21 and JWB. It revealed an acute stress reaction in non-frontline pediatric nurses and recommends more focus on the factors influencing the SASRQ.
ABSTRACT
Background/Objective: Fever is one of the commonest symptoms in children, and accounts for one third of the common clinical symptoms of childhood diseases. Most cases of pediatric fever were related to viral infection, especially during the COVID-19 pandemic. This randomized controlled trial aimed to establish specialist nurse-led territory nosocomial infection-control practice, and to evaluate the effect of this practice in a pediatric fever clinic. Methods: Scores of nosocomial infection-prevention and control knowledge of staff in different positions at the fever clinic and the quality of nosocomial infection prevention and control in fever clinic from before to after implementation of the intervention were compared. Participants were the staff of a fever clinic in a tertiary children's hospital in China. We adopted routine nosocomial infection-control practices before the implementation (April−August 2021) and then a Specialist-Nurse-led Infection-control Practices from October 2021 to February 2022. Results: The score of nosocomial infection-prevention and control knowledge of staff in different positions of the fever clinic improved from 77.16±13.372 to 93.51±8.429. The quality score improved from 85.70±3.420 to 94.20±2.191 after the intervention. The difference was statistically significant (P < 0.05). Conclusions: Specialist nurse-led territory nosocomial infection-control practice can effectively improve the staff's knowledge and the quality of nosocomial infection prevention and control in pediatric fever clinics.
Subject(s)
Fever , Cross Infection , Virus Diseases , Pediatric Obesity , COVID-19ABSTRACT
The dominant N501Y mutation in the spike protein that SARS-CoV-2 virus uses to bind to the human ACE2 receptor were found in the UK, which has aroused global concern and worried. Mutations in spike protein may, in theory, result in more infectious and spreading more easily. In order to evaluate the broad-spectrum protective effect of the monoclonal antibodies(mAbs), we compared the neutralization activities of six prepared mAbs against SARS-CoV-2 with pseudovirus neutralization assay. Only one of them showed a decrease of 6 folds in neutralizing activity to N501Y mutant strain, compared with the wild type strain. We should continue to monitor emergence of new variants in different regions to study their infectivity and neutralization effect.